What is the science behind CoronaOven? - CoronaOven Scroll to top

What is the science behind CoronaOven?

The method by which a UV light renders a virus such as Coronaviruses inactive is as following

Upon exposing a virus to UV light, the UV light penetrates the virus shell and reaches to the virus RNA or DNA. A virus RNA or DNA is like a long-stretched rope with ladder steps on it. These ladders are called nucleotides. UV light of a particular dose causes photochemical fusion of two nucleotides which are close to each other. This photochemical fusion is like chemically welding of nucleotides which permanently damages the RNA or DNA of the virus and hence renders them inactive. For more detailed study on this

subject please visit https://www.ncbi.nlm.nih.gov/pubmed/10827179

We can look to previous coronaviruses, such as SARS and MERS, for insight. Studies on both SARS and MERS show that UV light could inactivate these viruses.

To inactivate viruses using UV light two key aspects are important.

  1. Selection of appropriate UV light wavelength to which a virus is susceptible
  2. Generating appropriate UV light exposure such that it causes the necessary damage to the genetic material (DNA or RNA) of a virus.  

A team at the university of Nebraska Medical Center recently evaluated Ultraviolet Germicidal Irradiation (UVGI) and its effect on  Decontamination and Reuse of N95 Filtering Facepiece Respirators where they reported literature references supporting that  UVGI exposures of 1 J/cm2 are capable of decontaminating influenza virus on N95 FFRs and exposures as low as of 2-5 mJ/cm2 are capable inactivating coronaviruses on surfaces. [2],[3]. The Nebraska Medical Center evaluated UVGI exposure in the range of 60 mJ/cm2 to 300 mJ/cm2 and reported that UVGI exposures were validated to reduce 6 log of bacterial and viral surrogate organisms [4].US FDA and NIH also investigated these two aspects of UV light on inactivating Coronavirus called the SARS-CoV1 virus [5]. In short, the FDA and NIH study showed thatUV light with a wavelength of 254 nm could create enough damage to the RNA of Coronavirus (SARS-CoV1) rendering the virus inactive. SARS-CoV1 is closestvirus to COVID – 19 (SARS-CoV2). Both viruses have similar genetic molecules (RNA) and has approximately same size, shape and outer covering shell making them susceptible to similar damage profile caused by UVC light. Different viruses are sensitive to different UVexposure which were extensively detailed by Kowalski et al [6]. Moreover Eickmann et. al [7] published data on inactivation of Coronaviruses in platelet concentrates and plasma .

CoronaOven is specifically designed and calibrated as per the above-mentionedstudies to deliver the recommended UVC wavelength and the recommended UVC dose per cm2 on the surface of an object placed inside the Oven. Moreover, CoronaOven’s unique 360-degree illumination design ensures that each point on the surface of an object placed inside the CoronaOven receives the required wavelength and the required UV dose without generation of a shadow area. At Log9 we have extensively tested the performance of the CoronaOven using light wave simulation and actual meter reading to confirm that the necessary wavelength and energy is maintained on the surface of an object placed inside it. Our light dosimetry calculation confirms that in a short time exposure, each object placed inside the CoronaOven receives the necessary UVC dose as detailed out by the above-mentioned research papers. At Log9 we are committed to bringing scientific and safe solutions to our collective fight against COVID-19. The CoronaOven is expected to reduce the surface to human infection both at the front-line hospitals for our doctors and healthcare staff and at home.

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